A Stochastic Compartmental Model for Fast Axonal Transport

In this paper we develop a probabilistic micro-scale compartmental model and use it to study macro-scale properties of axonal transport, the process by which intracellular cargo is moved in the axons of neurons. By directly modeling the smallest scale interactions, we can use recent microscopic experimental observations to infer all the parameters of the model. Then, using techniques from probability theory, we compute asymptotic limits of the stochastic behavior of individual motor-cargo complexes, while also characterizing both equilibrium and non-equilibrium ensemble behavior. We use these results in order to investigate three important biological questions: (1) How homogeneous are axons at stochastic equilibrium? (2) How quickly can axons return to stochastic equilibrium after large local perturbations? (3) How is our understanding of delivery time to a depleted target region changed by taking the whole cell point-of-view

The application of a Mach-Zehnder interferometer to two channel spatial filtering

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Rural-Urban Variations in Meals on Wheels Programs

Older adults are living longer than ever before. By 2060, the U.S. population aged 65 or older is projected to reach 98 million. As adults age, the prevalence of chronic diseases and disabilities increases. The need for Meals on Wheels (MOW) services is growing alongside the aging population. Yet, little is known about the geographic variation of services. Little is documented about the organizational capacity of MOW organizations in terms of geography. The current policies supporting home-and community-based services, including MOW, may be insufficient to support all older adults in all types of communities. An analysis of the More Than a Meal® Comprehensive Network Study was conducted to determine geographic variation in services delivered through MOW programs and to document organizational capacity by geography. Chi-squared analyses were performed to identify relationships between twenty services offered through MOW organizations and categorial offerings within nutrition, in-home safety, socialization, and community connections categories. Spidergrams were created to document organizational capacity holistically and for three individual organizations for each of the geographic areas: Rural Only, Partial Rural, and Non-rural Service Areas. Using these findings, a policy analysis was conducted to determine policy recommendations to inclusively support rural older adults. Older adults living in rural areas access the full complement of services provided by MOW programs differently than do their non-rural counterparts. Specifically, a statistically significant relationship was found between the stratified component of in-home safety for rural, partial rural and non-rural service areas. When evaluated on the individual service offering level, statistically significant relationships between rurality and congregate meals, nutrition education, nutrition assessment, coordination of USDA food assistance programs, and telephone reassurance were seen. Spidergram documentation of capacity created visual representations of geographic similarities and differences. The policy analysis produced three potentially viable policy additions for the Older Americans Act around a provision for innovation programs, a report on in-home safety, and business acumen provisions. This work lays the foundation for further analysis of existing data with a lens of geographic specificity, as well as articulates the importance of looking at organizational capacity as a part of policy recommendations for understanding rural community-based organizations

An Analysis of 35 Consecutive Cases of Bradycardia.

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Between Iraq and a Hard Place: The U.N. Compensation Commission and Its Treatment of Gulf War Claims

The United Nations Compensation Commission (UNCC) was formed in 1991 to address claims against Iraq arising out of the Gulf War. In its seven years of operation, the UNCC has received 2.6 million claims, with an asserted value of more than $244 billion. It has processed 2.4 million of these claims, for a total of$6 billion, and it has paid to victims more than $730 million. Despite these accomplishments, the UNCC has much left to do, and its efforts have been burdened by Iraq\u27s post-war refusal to meet its treaty obligations. The UNCC now faces waning political support from U.N. members, who themselves face increasing pressure from the international business community to reintegrate Iraq into the world economy. This Note discusses the response of the United Nations to Iraq\u27s invasion of Kuwait, including the formation of the UNCC. It describes the structure and composition of the UNCC and the procedures it has developed for addressing claims. This Note also evaluates the UNCC\u27s progress since 1991, with particular attention to the political and commercial forces that now threaten its mission. Finally, this Note concludes that, despite international political sentiments ranging from apathy to hostility, the United Nations must reaffirm its commitment to international accountability generally, and to the victims of the Gulf War in particular, by continuing to support the UNCC

The School Library--The Alpha and Omega of your Elementary School Reading Program

No child in your school is ever too young to be introduced to the magic place called the library. Kindergartners in particular need to be surrounded with books, books and more books if we expect them to develop voracious appetites for the printed word. All children need to be saturated daily with stories which will stimulate their imagination and keep their curiosities amply nourished. For instance, an appreciation and sense oflanguage and word power can be cultivated very satisfactorily through the use of Mother Goose rhymes. The musical quality of these rhymes has rarely ever failed to tickle children\u27s ears. Before long then, they will be eager participants who find great delight in letting even the more difficult words roll across their tongues easily and expertly

Nitroglucose

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On allotropic silver

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